Cas No.: | 1230487-00-9 |
Chemical Name: | 1-[[4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]-2-ethylphenyl]methyl]azetidine-3-carboxylic acid |
Synonyms: | Siponimod; Siponimod [INN]; BAF-312, BAF 312 |
SMILES: | N(CC1=CC=C(/C(=N/OCC2=CC=C(C3CCCCC3)C(C(F)(F)F)=C2)/C)C=C1CC)1CC(C(O)=O)C1 |
Formula: | C29H35F3N2O3 |
M.Wt: | 516.59501 |
Sotrage: | 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO |
Description: | Siponimod (BAF-312) is a potent and selective sphingosine-1-phosphate (S1P) receptor modulator. It is selective for S1P1 and S1P5 receptors over S1P2, S1P3, and S1P4 (EC50s of 0.39, 0.98, >10,000, >1,000, and 750 nM, respectively.) |